1. Für Posterpräsentatoren: Die Größe der Posterboards beträgt 150 cm (hoch) x 120 cm (breit) (Hochformat). Die Posterabstracts finden Sie unter dem Link https://www.dropbox.com/sh/vte7m53fyldy9p9/AAAjSwIQrKFTnvOW1bdAiwpwa?dl=0 . Die Posterboards werden nummeriert sein, Ihre Bordnummer finden Sie auf der vor Ort aufliegenden Posterliste. 

2. Abstracts: 

Abstracts für Posterpräsentationen (in englischer Sprache) bitte per Email an office@brainplatform.net. Folgendes Format ist zwingend notwendig, da angestrebt wird, die Abstracts in Pharmacopsychiatry zu publizieren:

Sprache: Englisch
MS Word Dokument (*.doc, *.docx)
Schrift Arial 12 pt
Maximal 250 Wörter plus Titel und Autoren

Abstracts werden vom Programmkomitee evaluiert und sind erst nach Rückbestätigung per Email als angenommen zu betrachten 

Deadline für Einreichung von Abstracts: 15. April 2018 

Beispielabstract (von TDM Symposium 2016): 

TDM of psychotropic drugs in body fluids

Braun D., Stegmann B., Haen E. 

Klinische Pharmakologie am Lehrstuhl für Psychiatrie und Psychotherapie und am Lehrstuhl für Pharmakologie und Toxikologie, University of Regensburg, Germany

In therapeutic drug monitoring (TDM) serum or plasma is an often utilized biological matrix. Investigations on less invasive body fluids like saliva or urine are an important issue, as there are practical problems with blood testing especially with children.
If saliva would be used in TDM, the saliva to plasma concentration ratio should be constant over a wide plasma concentration range. This correlation was shown for some anticonvulsant drugs like phenytoin and carbamazepine. Other active substances like the psychostimulants methylphenidate and dexamphetamine show highly variable ratios of saliva to plasma concentration, depending on the salivary pH and the plasma protein binding of the drug. In that case saliva samples are useful for qualitative detection of drugs and for assuring compliance, but not for optimizing an existing pharmacotherapy by TDM.
Urine is suitable for controlling compliance and for testing drug abuse, as many drugs are detectable in it. However quantification of drugs in urine is problematic. Many factors like the hydration status of the body or the urinary pH influence the concentrations.
Another interesting body fluid for quantification of active substances is cerebrospinal fluid (CSF). Its normally low protein content simplifies sample preparation for HPLC. Furthermore CSF may reveal the presence of a psychotropic drug at the site of action. For example the neuroleptic drug olanzapine shows a clear-cut correlation between concentrations in serum and in CSF, indicating that serum concentrations of olanzapine reflect those in CSF.
In most instances serum or plasma is the most appropriate body fluid for TDM.


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